CAMP INDUCES LONG-TERM MORPHOLOGICAL-CHANGES IN SENSORY NEURONS OF APLYSIA

被引：73

作者：

NAZIF, FA ^{[1
]}

BYRNE, JH ^{[1
]}

CLEARY, LJ ^{[1
]}

机构：

[1] UNIV TEXAS,SCH MED,DEPT NEUROBIOL & ANAT,POB 20708,HOUSTON,TX 77225

来源：

BRAIN RESEARCH | 1991年 / 539卷 / 02期

关键词：

ADENOSINE MONOPHOSPHATE; CYCLIC; MORPHOLOGY; SENSORY NEURON; VARICOSITY; LONG-TERM MEMORY;

D O I：

10.1016/0006-8993(91)91638-H

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Long-term sensitization of defensive reflexes in the marine mollusc Aplysia has been correlated with biophysical changes in the somata of sensory neurons that mediate the reflexes 35 and with morphological changes in their axonal processes 2-4. The biophysical changes can also be mimicked by intracellular injection of cAMP 36. In this report we demonstrate that cAMP induces long-term structural changes in pleural sensory neurons, providing a mechanism for this form of memory storage.

引用

页码：324 / 327

页数：4

共 41 条

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