CYCLOADDUCTS OF ETHENE WITH 2(1H)-PYRAZINONES AND THEIR CONVERSION INTO 2,5-DIAZABICYCLO[2.2.2]OCTANE-3,6-DIONES

被引：23

作者：

LOOSEN, PK ^{[1
]}

TUTONDA, MG ^{[1
]}

KHORASANI, MF ^{[1
]}

COMPERNOLLE, F ^{[1
]}

HOORNAERT, GJ ^{[1
]}

机构：

[1] KATHOLIEKE UNIV LEUVEN,DEPT CHEM,ORGAN SYNTH LAB,CELESTIJNENLAAN 200F,B-3001 LOUVAIN,BELGIUM

来源：

TETRAHEDRON | 1991年 / 47卷 / 44期

关键词：

D O I：

10.1016/S0040-4020(01)96214-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cycloaddition of variously substituted 2(1H)-pyrazinones with ethene and subsequent hydrolysis of the adducts 2 provides a general and efficient route to the title compounds 3. Compound 3m was used as a building block for a structural analogue of gliotoxin.

引用

页码：9259 / 9268

页数：10

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