3-DIMENSIONAL STRUCTURES OF OLIGOSACCHARIDES

被引：61

作者：

WOODS, RJ

机构：

[1] Complex Carbohydrate Research Center, The University of Georgia, Athens, GA 30602-4712

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 05期

关键词：

D O I：

10.1016/0959-440X(95)80049-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Oligosaccharides represent a particularly challenging class of molecules for conformational analysis. Recent advances in experimental and theoretical methods have begun to yield further insight into their conformational behavior; however, general rules governing their conformational preferences have not yet emerged. X-ray and NMR techniques may provide vital insights into protein-bound oligosaccharide conformations, but these do not necessarily represent highly populated solution conformations. Moreover, an oligosaccharide's inherent flexibility and lack of strong intermolecular interactions places extreme demands on theoretical methods.

引用

页码：591 / 598

页数：8

共 94 条

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