CURVED DNA WITHOUT AA/TT DINUCLEOTIDE STEP

被引：22

作者：

BRUKNER, I ^{[1
]}

JURUKOVSKI, V ^{[1
]}

KONSTANTINOVIC, M ^{[1
]}

SAVIC, A ^{[1
]}

机构：

[1] UNIV BELGRADE, FAC SCI, DEPT BIOL, BELGRADE, YUGOSLAVIA

来源：

NUCLEIC ACIDS RESEARCH | 1991年 / 19卷 / 13期

关键词：

D O I：

10.1093/nar/19.13.3549

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The evidence is accumulating that dinucleotide steps other than AA/TT affect DNA flexure of A(n)T(m) (m + n > = 4) containing fragments. However, it is not clear whether macroscopic DNA flexure without AA/TT steps might occur. In this paper we demonstrate the anomaly in electrophoretic mobility of non AA/TT repetitive DNA sequences which is a function of sequence phasing. Therefore, our results show that PyPu (TA) and AG/CT steps, angulary separated by close to 180 degrees from Pu/Py (GC) and GG/CC steps, bend DNA, even in the absence of A(n)T(m) tracts.

引用

页码：3549 / 3551

页数：3

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