STEREOSELECTIVE SYNTHESIS OF 4-SUBSTITUTED OR 5-SUBSTITUTED 2-BENZYLPYRROLIDINES AND 2-BENZOYLPYRROLIDINES BY MEANS OF ANODIC-OXIDATION OF DELTA-ALKENYLAMINES

被引：39

作者：

TOKUDA, M

MIYAMOTO, T

FUJITA, H

SUGINOME, H

机构：

[1] Organic Synthesis Division, Faculty of Engineering, Hokkaido University, Sapporo

来源：

TETRAHEDRON | 1991年 / 47卷 / 4-5期

关键词：

D O I：

10.1016/S0040-4020(01)87064-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The anodic oxidation of the lithium amides of delta-alkenylamines 6a, 6b, 6c, 10a, and 10b gave stereoselectively cis-5-substituted 2-benzyl-1-methylpyrrolidines (7a, 7b, 7c) and 4-substituted 2-benzyl-1-methyl-pyrrolidines (11a, 11b) in high yields. The anodic oxidation of N-methoxyl compounds of delta-alkenylamines (12a, 12b) gave 5-substituted 2-benzoyl-1-methylpyrrolidines (13a, 13b).

引用

页码：747 / 756

页数：10

共 39 条

[1]

ADAMS R, 1932, ORG SYNTH, V1, P250

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