DEPOT ANTIPSYCHOTICS IN BIPOLAR AFFECTIVE-DISORDER

被引：75

作者：

WHITE, E ^{[1
]}

CHEUNG, P ^{[1
]}

SILVERSTONE, T ^{[1
]}

机构：

[1] UNIV OTAGO,SCH MED,DEPT PSYCHOL MED,DUNEDIN,NEW ZEALAND

来源：

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1993年 / 8卷 / 02期

关键词：

ANTIPSYCHOTICS; BIPOLAR DISORDER; DEPOT; DEPRESSION; MANIA; PROPHYLAXIS;

D O I：

10.1097/00004850-199300820-00007

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effect of prophylactic treatment with depot antipsychotic drugs was examined in 16 patients with bipolar affective disorder. The frequency and duration of illness episodes occurring during depot treatment was compared to that which occurred when these patients were treated with other agents over a corresponding time period. Treatment with depot antipsychotics was associated with a significant decrease in the frequency and duration of manic episodes, but not depressive episodes. Thus prophylactic treatment with depot antipsychotic drugs is likely to be of benefit in patients with bipolar illness who experience frequent manic episodes despite treatment with lithium and/or carbamazepine.

引用

页码：119 / 122

页数：4