SYNTHESIS AND CONFORMATIONAL BEHAVIOR OF NOVEL CYCLODEXTRIN HETERO-DIMERS

被引：28

作者：

VENEMA, F ^{[1
]}

BASELIER, CM ^{[1
]}

FEITERS, MC ^{[1
]}

NOLTE, RJM ^{[1
]}

机构：

[1] UNIV NIJMEGEN,NSR CTR,DEPT ORGAN CHEM,6525 ED NIJMEGEN,NETHERLANDS

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(00)78465-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of two novel cyclodextrin heterodimers derived from alpha- and beta-cyclodextrin is reported. The cyclodextrin molecules are linked via alkyl spacers on their secondary sides. NMR-studies indicate that the spacer is bound in one of the two cavities of the dimer, which results in lower affinities for guest molecules.

引用

页码：8661 / 8664

页数：4

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