BIOCHEMICAL-ABNORMALITIES OF THE HUMAN DIABETIC GLOMERULAR BASEMENT-MEMBRANE

被引：20

作者：

CANIVET, J

CRUZ, A

MOREAULALANDE, H

机构：

[1] Department of Endocrinology and Metabolism, Hopital Saint Louis, Université Paris

来源：

METABOLISM-CLINICAL AND EXPERIMENTAL | 1979年 / 28卷 / 12期

关键词：

D O I：

10.1016/0026-0495(79)90132-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Since the biochemical composition of the diabetic glomerular basement membrane is still a controversial area, a study was carried out using kidneys from seven diabetic and seven nondiabetic subjects. In diabetic membranes, the glycine, hydroxylysine, glucose, galactose, and hydroxylysine-linked disaccharide unit content was increased together with a decrease in the half-cystine and sialic acid content. These findings support the view of a biochemical alteration in the human diabetic glomerular basement membrane. © 1979.

引用

页码：1206 / 1210

页数：5

共 18 条

[1] STUDIES ON HUMAN GLOMERULAR BASEMENT-MEMBRANE - COMPOSITION, NATURE OF CARBOHYDRATE UNITS AND CHEMICAL CHANGES IN DIABETES-MELLITUS [J].