DETERMINANTS OF PLASMA VITAMIN-E CONCENTRATIONS

被引：101

作者：

TRABER, MG

机构：

[1] Department of Medicine, New York University School of Medicine, New York, NY

来源：

FREE RADICAL BIOLOGY AND MEDICINE | 1994年 / 16卷 / 02期

关键词：

ALPHA-TOCOPHEROL; GAMMA-TOCOPHEROL; ALPHA-TOCOTRIENOL; CHYLOMICRONS; VLDL; LDL; HDL; HEPATIC TOCOPHEROL BINDING PROTEIN; ISOLATED VITAMIN-E DEFICIENCY; BIOLOGIC ACTIVITY; FREE RADICALS;

D O I：

10.1016/0891-5849(94)90148-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vitamin E, a lipid soluble antioxidant, is transported in plasma lipoproteins. This review will summarize the mechanisms for the preferential incorporation of RRR-alpha-tocopherol into lipoproteins. Special attention is devoted to the hepatic tocopherol binding protein, and to patients who are vitamin E deficient because they apparently have a genetic defect in this protein. The regulation of plasma vitamin E by the tocopherol binding protein as a determinant of the biologic activity of various forms of vitamin E is also discussed.

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页码：229 / 239

页数：11

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