ELENIC ACID, AN INHIBITOR OF TOPOISOMERASE-II, FROM A SPONGE, PLAKINASTRELLA SP

被引:20
作者
JUAGDAN, EG
KALIDINDI, RS
SCHEUER, PJ
KELLYBORGES, M
机构
[1] UNIV HAWAII MANOA,DEPT CHEM,HONOLULU,HI 96822
[2] HARBOR BRANCH OCEANOG INST INC,FT PIERCE,FL 34936
关键词
D O I
10.1016/0040-4039(95)00432-C
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Elenic acid (R-2,4-dimethyl-22-(p-phydroxyphenyl)-docos-3(E)-enoic acid) from an Indonesian sponge, Plakinastrella sp. inhibits Topoisomerase II with an IC50 of 0.1 mu g/mL.
引用
收藏
页码:2905 / 2908
页数:4
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