DERIVATIVES OF IMIDAZOLE .3. SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF NITRILES AMIDES AND CARBOXYLIC ACID DERIVATIVES OF IMIDAZO(1,2-A)PYRIDINE

被引：31

作者：

ALMIRANTE, L

MUGNAINI, A

RUGARLI, P

GAMBA, A

ZEFELIPPO, E

DETOMA, N

MURMANN, W

机构：

[1] Research Department, Selxi e C, Laboratorio Bioterapico Milanese, Milan

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 01期

关键词：

D O I：

10.1021/jm00301a031

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A number of improved laboratory procedures for the synthesis of imidazol [1,2-a]pyridine derivatives are reported. The resulting compounds, which are structurally related to indole derivatives, have been screened for analgetic, antipyretic, anticonvulsant, and antiinflammatory activity. Phytopharmacological tests have also been performed on the derivatives structurally related to indoleacetic acid. © 1969, American Chemical Society. All rights reserved.

引用

页码：122 / +

页数：1

共 17 条

[1] DERIVATIVES OF IMIDAZOLE .2. SYNTHESIS AND REACTIONS OF IMIDAZO[1,2-A]PYRIMIDINES AND OTHER BI- AND TRICYCLIC IMIDAZO DERIVATIVES WITH ANALGESIC ANTIINFLAMMATORY ANTIPYRETIC AND ANTICONVULSANT ACTIVITY
ALMIRANTE, L
POLO, L
MUGNAINI, A
PROVINCIALI, E
RUGARLI, P
GAMBA, A
OLIVI, A
MURMANN, W
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1966, 9 (01) : 29 - +
[2] DERIVATIVES OF IMIDAZOLE .I. SYNTHESIS AND REACTIONS OF IMIDAZO[1,2-A]PYRIDIENES WITH ANALGESIC ANTIINFLAMMATORY ANTIPYRETIC AND ANTICONVULSANT ACTIVITY
ALMIRANTE, L
POLO, L
MUGNAINI, A
PROVINCIALI, E
RUGARLI, P
BIANCOTTI, A
GAMBA, A
MURMANN, W
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1965, 8 (03) : 305 - +
[3] ALMIRANTE L, 1966, B CHIM FARM, V105, P32
[4] IMIDAZO[1,2-A]PYRIDINIUM SALTS
BRADSHER, CK
LITZINGE.EF
ZINN, MF
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1965, 2 (04) : 331 - &
[5] BUUHOI NP, 1949, RECL TRAV CHIM PAY B, V68, P441
[6] PREPARATION AND NEW REACTIONS OF IMIDAZO[1,2-A]PYRIDINES
LOMBARDINO, JG
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1965, 30 (07) : 2403 - +
[7] AROMATICITY IN HETEROCYCLIC SYSTEMS .3. STRUCTURE AND PROTON MAGNETIC RESONANCE SPECTRA OF CERTAIN IMIDAZO[1,2-A]PYRIDINES
PAOLINI, JP
ROBINS, RK
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1965, 2 (01) : 53 - &
[8] AROMATICITY IN HETEROCYCLIC SYSTEMS .4. SUBSTITUTION REACTIONS OF IMIDAZO[1,2-A]PYRIDINE AND RELATED METHYL DERIVATIVES
PAOLINI, JP
ROBINS, RK
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1965, 30 (12) : 4085 - &
[9] 10 PI ELECTRON NITROGEN HETEROCYCLIC COMPOUNDS .V. SITE OF PROTONATION AND N-METHYLATION OF IMIDAZO[1,2-A]PYRIDINES AND PLANARITY OF RING SYSTEM
PAUDLER, WW
BLEWITT, HL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1966, 31 (04) : 1295 - &
[10] 10 PI-ELECTRON NITROGEN HETEROCYCLIC COMPOUNDS .2. BROMINATION OF IMIDAZO[1,2-A]PYRIDINES
PAUDLER, WW
BLEWITT, HL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1965, 30 (12) : 4081 - &

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