SYNTHESIS OF B/C TRANS-FUSED MORPHINE STRUCTURES .2. HYDROBORATION OF ISONEOPINE NEOPINE NEOPINONE AND THEBAINE

被引：19

作者：

TAKEDA, M

INOUE, H

KUGITA, H

机构：

[1] Research Laboratories, Tanabe Seiyaku Co. Ltd., Toda, Saitama

来源：

TETRAHEDRON | 1969年 / 25卷 / 09期

关键词：

D O I：

10.1016/S0040-4020(01)82805-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hydroboration of isoneopine gave (-)-3-methoxy-6β,8α-dihydroxy-4,5α-epoxy-N-methylisomorphinan (II) in good yield, while hydroboration of neopine gave very low yields of two dihydroxy derivatives isomeric with II. Neopinone gave II and neopine. Hydroboration of thebaine, a cyclic diene system, was also examined. © 1969.

引用

页码：1839 / &

共 16 条

[1] DIMETHYL SULFOXIDE-ACID ANHYDRIDE MIXTURES FOR OXIDATION OF ALCOHOLS [J].