BODY-MASS AND PHYSICAL-ACTIVITY ARE IMPORTANT PREDICTORS OF SERUM ANDROGEN CONCENTRATIONS IN YOUNG HEALTHY-MEN

被引：34

作者：

MANTZOROS, CS ^{[1
]}

GEORGIADIS, EI ^{[1
]}

机构：

[1] MIL HOSP 401,ENDOCRINE UNIT,ATHENS,GREECE

来源：

EPIDEMIOLOGY | 1995年 / 6卷 / 04期

关键词：

TESTOSTERONE; SEX HORMONE-BINDING GLOBULIN; DEHYDROEPIANDROSTERONE SULFATE; DIHYDROTESTOSTERONE; PHYSICAL ACTIVITY; BODY MASS INDEX;

D O I：

10.1097/00001648-199507000-00020

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The relative importance of body mass index (BMI), demographic, and life style factors in predicting androgen and sex hormone binding globulin (SHBG) concentrations of young healthy men has not been clearly established. We evaluated the role of age, BMI, height, habitual physical activity, education, smoking, coffee and alcohol intake as predictors of serum testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, androstenedione, and SHBG concentrations in 100 healthy men 18-22 years old. BMI was the only independent predictor of dihydrotestosterone and dehydroepiandrosterone sulfate, and both BMI and physical activity were independent predictors of serum testosterone concentrations, whereas other variables did not appear to play a role of comparable importance.

引用

页码：432 / 435

页数：4

共 42 条

[1] Suh I., Shater B.J., Butler J.A., Kuller L.H., Alcohol use and mortality from coronary heart disease: The role of high-density lipoprotein cholesterol, Ann Intern Med, 116, pp. 881-887, (1992)
[2] Rodriguez B.L., Curb J.D., Burchtiel C.M., Abhott R.D., Petrovich H., Masaki K., Chiu D., Physical activity and 23 year tncidence of coronary heart disease morbidity and mortality among middle-aged men: The Honolulu Heart Program, Circulation, 89, pp. 2540-2544, (1994)
[3] Bardin C.W., Swerdloff R.S., Santen R.J., Androgens: Risks and benefits, J Clin Endocrinol Metab, 73, pp. 4-7, (1991)
[4] Bagatell C.G., Knopp R.H., Vale W.W., Rivier J.E., Bremmer W.J., Physiologie testosterone levels in normal men suppress high density lipoprotein cholesterol levels, Ann Intern Med, 116, pp. 967-973, (1992)
[5] Chute C., Baron J.A., Plymate S.R., Kiel D.P., Pavia A.T., Loiner E.Z., O'Keefe T., McDonald G.J., Sex hormones and coronary artery disease, Am J Med, 83, pp. 853-859, (1987)
[6] Pasquali R., Casimirri F., Cantobelli S., Melchtonda N., Labate A., Fabbri R., Capelli M., Botroluzzi L., Effect of obesity and body fat distribution on sex hormones and insulin in men, Metabolism, 40, pp. 101-104, (1991)
[7] Gittes R.F., Cancer of the prostate, N Engl J Med, 324, pp. 236-245, (1991)
[8] Kato I., Nomura A., Stemmermann G.N., Chyou P.H., Determinants of sex hormone levels in men as useful indices in hormone-related disorders, J Clin Epidemiol, 45, pp. 1417-1421, (1992)
[9] Mancini G.B.J., More bad news for couch potatoes and smokers who atone through exercise, Lancet, 344, pp. 629-630, (1994)
[10] Tsitouras P., Effects of age on testicular function, Endocrinol Metab Clin North Am, 16, pp. 1045-1059, (1987)

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