CHARACTERIZATION OF THE CAPSULAR ANTIGEN OF STREPTOCOCCUS-PNEUMONIAE SEROTYPE 35B

被引：6

作者：

BEYNON, LM

RICHARDS, JC

PERRY, MB

KNISKERN, PJ

机构：

[1] NATL RES COUNCIL CANADA,INST BIOL SCI,OTTAWA,ON K1A 0R6,CANADA

[2] MERCK SHARP & DOHME LTD,RES LABS,W POINT,PA 19486

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1995年 / 73卷 / 01期

关键词：

STREPTOCOCCUS PNEUMONIAE; CAPSULAR ANTIGEN; POLYSACCHARIDE STRUCTURE;

D O I：

10.1139/v95-006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The specific capsular antigen of Streptococcus pneumoniae serotype 35B was shown by a combination of 2D NMR methods and mass spectrometric and classical carbohydrate chemical techniques to be a high molecular weight polymer containing D-galactose, D-glucose, 2-acetamido-2-deoxy-D-galactose, and ribitol (2:1:1:1). The pentasaccharide repeating unit is polymerized through phosphate diester linkages to give the structure, [GRAPHICS] Seventy percent of the beta-D-Gal(f) residues glycosidically linked to the ribitol units carry an O-acetyl substituent.

引用

页码：41 / 48

页数：8

共 21 条

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