CD11/CD18 PANEL REPORT FOR SWINE CD WORKSHOP

被引：14

作者：

KIM, YB

ZHANG, J

DAVIS, WC

LUNNEY, JK

机构：

[1] WASHINGTON STATE UNIV,COLL VET MED,PULLMAN,WA 99164

[2] USDA ARS,LPSI,HELMINTH DIS LAB,BELTSVILLE,MD 20705

来源：

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 1994年 / 43卷 / 1-3期

关键词：

D O I：

10.1016/0165-2427(94)90150-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Five monoclonal antibodies (mAbs), PNK-I (W #037), H20A (W #077), MUC76A (W #078), MVC93A (W #079) and MHM23 (W #136) of CD11/18 panels reacted with 80-96% of porcine PBMC and PMN. Epitope mapping studies by competitive binding of mAb by flow cytometric analysis based on PNK-I as CD18 epitope defining antibody resulted H20A and MHM23 mAbs bind to the same shared epitope as PNK-I, but MUC76A and MUC93A mAbs were distinct from PNK-I. Thus, PNK-I, H20A and MHM23 were designated as CD18a mAbs.

引用

页码：289 / 291

页数：3

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