REACTIONS OF HYDROXYLAMINES WITH ETHYL CYANOFORMATE - PREPARATION OF AMINONITRONES AND THEIR SYNTHETIC APPLICATIONS

被引：46

作者：

BRANCO, PS

PRABHAKAR, S

LOBO, AM

WILLIAMS, DJ

机构：

[1] UNIV NOVA LISBOA,DEPT QUIM,SECCAO QUIM ORGAN APLICADA,CAMPUS FCT-UNL,QUINTA TORRE,P-2825 MONTE DE CAPARICA,PORTUGAL

[2] INST NACL INVEST CIENTIF,CTR QUIM ESTRUTURAL,P-1096 LISBON,PORTUGAL

[3] UNIV NOVA LISBOA,SINTOR,P-2825 MONTE DE CAPARICA,PORTUGAL

来源：

TETRAHEDRON | 1992年 / 48卷 / 30期

关键词：

ETHYL CYANOFORMATE; HYDROXYLAMINE; ALPHA-AMINONITRONE; NITROGEN HETEROCYCLES;

D O I：

10.1016/S0040-4020(01)88224-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of hydroxylamines with ethyl cyanoformate 1 leads to the formation of carbethoxyamino nitrones 2. UV spectroscopy provided information that suggested the nitrone structure for these compounds in solution. X-ray analysis of 2a confirmed that it exists entirely in the nitrone form in the solid state. These nitrones are shown to be excellent starring materials for a variety of nitrogen containg compounds, namely, imidazoles. benzimidazoles, benzimidazolones, oxadiazolones, N-arylamidines and quinoxalone.

引用

页码：6335 / 6360

页数：26

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