SEA URCHIN NUCLEAR DNA POLYMERASE .I. LOCALIZATION IN NUCLEI DURING RAPID DNA SYNTHESIS

被引：49

作者：

LOEB, LA

FANSLER, B

WILLIAMS, R

MAZIA, D

机构：

[1] The Department of Zoology, University of California, Berkeley

来源：

EXPERIMENTAL CELL RESEARCH | 1969年 / 57卷 / 2-3期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0014-4827(69)90153-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A direct comparison was made between the DNA polymerase activity of isolated nuclei and the sea urchin embryos from which they were derived. The nuclei, which were isolated by simple aqueous techniques, contained 56 to 95% of the total DNA polymerase activity of the hatched embryos. It is concluded that sea urchin embryo DNA polymerase, an enzyme preferentially primed by native DNA, is strongly associated with nuclei at the stage of hatching, a period of rapid DNA synthesis. © 1969.

引用

页码：298 / &

共 18 条

[1]

APOSHIAN HV, 1962, J BIOL CHEM, V237, P519

[2] INHIBITION OF DEOXYRIBONUCLEOTIDYL TRANSFERASE DNAASE AND RNAASE BY SODIUM POLY ETHENESULFONIC ACID . EFFECT OF MOLECULAR WEIGHT OF INHIBITOR [J].