SINGLE INJECTION TREATMENT OF MENINGOCOCCAL MENINGITIS .2. LONG-ACTING CHLORAMPHENICOL

被引：41

作者：

WALI, SS ^{[1
]}

MACFARLANE, JT ^{[1
]}

WEIR, WRC ^{[1
]}

CLELAND, PG ^{[1
]}

BALL, PAJ ^{[1
]}

HASSANKING, M ^{[1
]}

WHITTLE, HC ^{[1
]}

GREENWOOD, BM ^{[1
]}

机构：

[1] AHMADU BELLO UNIV, ZARIA, NIGERIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1979年 / 73卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0035-9203(79)90024-5

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A single injection of a long-acting oily preparation of chloramphenicol (Tifomycine) was compared with a five-day course of crystalline and procaine penicillin in the treatment of 131 adult patients with meningococcal meningitis. The clinical response to treatment was similar in the two groups of patients. Serial lumbar punctures showed a parallel fall in CSF cell count, protein and lactate and all post-treatment cultures were sterile. Single injection chloramphenicol treatment was cheaper and much easier to administer than penicillin. Long-acting chloramphenicol is thus an effective form of treatment for meningococcal meningitis and is likely to prove of particular value in the management of epidemics in areas with limited medical resources. © 1979 Oxford University Press.

引用

页码：698 / 702

页数：5

共 15 条

[1]

ESSAN GJF, 1973, W AFRICAN J S, V22, P534

[2] WARNING, CHLORAMPHENICOL MAY BE GOOD FOR YOUR HEALTH [J].