3-DIMENSIONAL INVIVO ESR IMAGING IN RATS

被引：64

作者：

ALECCI, M ^{[1
]}

COLACICCHI, S ^{[1
]}

INDOVINA, PL ^{[1
]}

MOMO, F ^{[1
]}

PAVONE, P ^{[1
]}

SOTGIU, A ^{[1
]}

机构：

[1] UNIV AQUILA,DIPARTIMENTO SCI & TECHNOL BIOMED,LOCALITA COLLEMAGIO,I-67100 AQUILA,ITALY

来源：

MAGNETIC RESONANCE IMAGING | 1990年 / 8卷 / 01期

关键词：

3D imaging; Electron spin resonances; Free radicals; In vivo; Nitroxides; Reconstruction from projections; Spin labels; Zeugmatography;

D O I：

10.1016/0730-725X(90)90213-L

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The first experiment of tridimensional in vivo ESR imaging at 1.2 GHz is described in this paper. The tails of rats weighing 300-350 grams were visualized using 1 cc of a 50 * 10-3 M solution of nitroxide free radical injected in the caudal vein. If an even distribution of spin label is assumed this would correspond to a final concentration of about 10-4 M. A reconstruction from projections was used to obtain the images. The apparatus utilizes stationary field gradients. Projections were obtained by sweeping the main field. For 3D reconstructions, the projections were collected along 32 * 8 field gradient orientations. The whole procedure takes approximately 18 minutes. © 1990.

引用

页码：59 / 63

页数：5

共 19 条

[1]

Berliner, Fujii, Wan, Lukiewicz, Feasibility study of imaging a living murine tumor by electron paramagnetic resonance, Magn. Reson. Med., 4, (1987)

[2]

Busse, Pratt, Thomas, Deconvolution of chemical shift spectra in two or three dimensional [<sup>19</sup>F] MR imaging: noise masked demodulation and maximum entropy deconvolution, J. Comput. Assist. Tomogr., 12, (1988)

[3]

Lai, True three-dimensional nuclear magnetic resonance imaging by Fourier reconstruction zeugmatography, J. Appl. Phys., 52, (1981)

[4]

Colacicchi, Indovina, Momo, Sotgiu, Low-frequency three-dimensional ESR imaging of large samples, J. Appl. Phys. E: Sci. Instrum., 21, (1988)

[5]

Eaton, Eaton, Electron spin-echo-detected EPR imaging, J. Magn. Reson., 59, (1984)

[6]

Ebert, Herrling, Numerical analysis in EPR zeugmatography, J. Magn. Reson., 61, (1985)

[7]

Fujii, Berliner, Application of the convolution difference resolution method in reconstruction techniques in EPR imaging, J. Magn. Reson., 68, (1986)

[8]

Herrling, Ewert, Schneider, Instrumentation and software for EPR imaging, 10th International EPR Symposium, Rocky Mountain Conference, (1987)

[9]

Hoch, Day, Imaging of paramagnetic centers in diamonds, Solid State Commun., 30, (1979)

[10]

Karthe, Wehrsdorfer, The measurement of inhomogeneous distribution of paramagentic centers by means of EPR, J. Magn. Reson., 33, (1979)

← 1 2 →