CLINICAL AND BIOCHEMICAL ASPECTS OF DEPRESSIVE-DISORDERS .2. TRANSMITTER RECEPTOR THEORIES

被引：127

作者：

CALDECOTTHAZARD, S

MORGAN, DG

DELEONJONES, F

OVERSTREET, DH

JANOWSKY, D

机构：

[1] UNIV CALIF LOS ANGELES, BIOMED & ENVIRONM SCI LAB, LOS ANGELES, CA 90024 USA

[2] UNIV SO CALIF, DEPT GERONTOL, LOS ANGELES, CA 90089 USA

[3] OLIVE VIEW MED CTR, DEPT PSYCHIAT, SYLMAR, CA 91342 USA

[4] UNIV N CAROLINA, CTR ALCOHOL STUDIES, CHAPEL HILL, NC 27599 USA

来源：

SYNAPSE | 1991年 / 9卷 / 04期

关键词：

DEPRESSIVE DISORDERS; NEUROTRANSMITTERS; RECEPTORS;

D O I：

10.1002/syn.890090404

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The present document is the second of three parts in a review that focuses on recent data from clinical and animal research concerning the biochemical bases of depressive disorders, diagnosis, and treatment. Various receptor/transmitter theories of depressive disorders are discussed in this section. Specifically, data supporting noradrenergic, serotonergic, cholinergic, dopaminergic, GABAergic, and peptidergic theories, as well as interactions between noradrenergic and serotonergic, or cholinergic and catecholaminergic systems are presented. Problems with the data and future directions for research are also discussed. A previous publication, Part I of this review, dealt with the classification of depressive disorders and research techniques for studying the biochemical mechanisms of these disorders. A future publication, Part III of this review, discusses treatments for depression and some of the controversies in this field.

引用

页码：251 / 301

页数：51

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