SYNTHETIC APPROACHES TO PHORBOLS VIA THE INTRAMOLECULAR DIELS-ALDER REACTIONS OF FURANS (IMDAF) - OXYGEN BRIDGE CLEAVAGE AND HIGH STEREOCONTROL DURING CYCLOADDITION USING ALPHA'-BENZYLTHIO SUBSTITUTED FURAN SUBSTRATES

被引：39

作者：

HARWOOD, LM ^{[1
]}

ISHIKAWA, T ^{[1
]}

PHILLIPS, H ^{[1
]}

WATKIN, D ^{[1
]}

机构：

[1] UNIV OXFORD,CHEM CRYSTALLOG LAB,OXFORD OX1 3PD,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 07期

关键词：

D O I：

10.1039/c39910000527

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High pressure mediated IMDAF of the alpha'-benzylthiofuran substrate 1 results in efficient and highly stereoselective cycloaddition; subsequent epimerisation of the cycloadduct 6 is regiospecific and the oxygen bridge may be opened by elimination or hydrolysis.

引用

页码：527 / 530

页数：4

共 11 条

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