IMPROVED SCREENING-PROCEDURE FOR DIURETICS

被引：13

作者：

HERRAEZHERNANDEZ, R

CAMPINSFALCO, P

SEVILLANOCABEZA, A

机构：

[1] Departamento de Química Analítica, Facultad de Química, Universidad de Valencia Burjassot, Valencia

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1992年 / 15卷 / 12期

关键词：

D O I：

10.1080/10826079208016335

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An improved screening procedure for commonly used diuretics in urine samples is described. The diuretics mixture assayed is quickly and satisfactorily resolved using an HP-Hypersil ODS-C18 column and a mobile phase consisting of acetonitrile/phosphate buffer (pH = 3) in gradient elution mode. Alternatively, acetate buffer (pH = 4) is utilized to improve resolution and sensitivity with more acidic compounds such as ethacrynic acid and probenecid.

引用

页码：2205 / 2224

页数：20

共 15 条

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