SEROLOGICAL EVALUATION OF THE 12-KDA SUBUNIT OF ANTIGEN-B IN ECHINOCOCCUS-GRANULOSUS CYST FLUID BY IMMUNOBLOT ANALYSIS

被引：55

作者：

LEGGATT, GR ^{[1
]}

YANG, W ^{[1
]}

MCMANUS, DP ^{[1
]}

机构：

[1] QUEENSLAND INST MED RES,BANCROFT CTR,TROP HLTH PROGRAM,300 HERSTON ROAD,BRISBANE,QLD 4029,AUSTRALIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1992年 / 86卷 / 02期

关键词：

D O I：

10.1016/0035-9203(92)90566-U

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

This study evaluated the 12 kDa (smallest) subunit of Echinococcus granulosus antigen B as a diagnostic molecule. Using immunoblotting, 90.9% of cystic hydatid patients, 40% of alveolar hydatid patients and 5.5% of cysticercosis patients showed sero-reactivity to this subunit. Human antibody response to the 12 kDa molecule appeared independent of factors such as parasite strain or host population responsiveness. The majority of infection sera, and some normal human controls, also recognized the 38 kDa subunit of antigen 5.

引用

页码：189 / 192

页数：4

共 17 条

[1]

CAPRON A, 1967, KYSTE HYDATIQUE FOIE, P27

[2] IDENTIFICATION AND CHARACTERIZATION OF ANTIGENIC COMPONENTS OF SHEEP HYDATID FLUID BY IMMUNOELECTROPHORESIS [J].