SYNTHESIS OF 1-PHENYL-2-(PHENYLCARBAMOYL)PYRAZOLIDINES AS POTENTIAL ANTICONVULSANT AGENTS

被引：22

作者：

KORNET, MJ

GARRETT, RJ

机构：

[1] College of Pharmacy, University of Kentucky, Lexington, Kentucky

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1979年 / 68卷 / 03期

关键词：

Anticonvulsant activity—various substituted pyrazolidines evaluated; Pyrazolidines; substituted—synthesized; anticonvulsant activity evaluated; Structure‐activity relationships—substituted pyrazolidines evaluated for anticonvulsant activity;

D O I：

10.1002/jps.2600680335

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Twelve 1‐phenyl‐2‐(phenylcarbamoyl)pyrazolidines were synthesized from 1‐arylpyrazolidines and aryl isocyanates. These adducts showed little anticonvulsant activity in the maximal electroshock seizure and pentylenetetrazol seizure assays. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：377 / 378

页数：2