GROUP-SPECIFIC COMPONENT (GC) POLYMORPHISM IN JAPANESE - ANALYSIS BY ISOELECTRIC-FOCUSING ON POLYACRYLAMIDE GELS

被引：22

作者：

ISHIMOTO, G ^{[1
]}

KUWATA, M ^{[1
]}

NAKAJIMA, H ^{[1
]}

机构：

[1] TOKYO MED & DENT UNIV,DEPT FORENS MED,TOKYO 113,JAPAN

来源：

JAPANESE JOURNAL OF HUMAN GENETICS | 1979年 / 24卷 / 02期

关键词：

D O I：

10.1007/BF01888924

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Using the immunofixation isoelectric focusing method, Gc subtypes were examined in the samples with the Gc J phenotypes previously determined by immunoelectrophoresis, and it was found that the GcJs are subdivided into 4 different alleles. A population study in sera from 1,041 individuals confirmed the presence of the 4 variant alleles with the frequencies between 0.020 for the highest allele and 0.001 for the lowest one. The distribution of Gc subtypes in a Japanese population and a pedigree study from 18 families with the propositus of the variant are presented along with a description of the 2 other variants observed in the course of this study. © 1979 Business Center for Academic Societies.

引用

页码：75 / 83

页数：9

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