WIDESPREAD INTRANUCLEAR NEURONAL CORPUSCLES (MARINESCO BODIES) ASSOCIATED WITH A FAMILIAL SPINAL DEGENERATION WITH CRANIAL AND PERIPHERAL-NERVE INVOLVEMENT

被引:38
作者
JANOTA, I [1 ]
机构
[1] BETHLEM ROYAL & MAUDSLEY HOSP,LONDON,ENGLAND
关键词
D O I
10.1111/j.1365-2990.1979.tb00630.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Case report. Widespread intranuclear neuronal corpuscles (Marinesco bodies) associated with a familial spinal degeneration with cranial and peripheral nerve involvement Widespread intranuclear, paranucleolar, acidophilic corpuscles, known as Marinesco bodies, were found in association with degeneration of the posterior columns of the spinal cord, posterior root ganglia and cranial nerves. The patient was a man dying at the age of 45 years. Neurological examination of his sister (aged 51 years) indicates that she is suffering from the same disease. The cases appear to belong to the predominantly spinal form of spino‐cerebellar degenerations or Friedreich's ataxia. This report, which includes an electron microscope examination, considers the pathological significance of Marinesco bodies. Copyright © 1979, Wiley Blackwell. All rights reserved
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页码:311 / 317
页数:7
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