POLYMERIC PHOSPHONIUM SALTS AS A NOVEL CLASS OF CATIONIC BIOCIDES .5. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF POLYESTERS RELEASING PHOSPHONIUM BIOCIDES

Polyesters were prepared which retained phosphonium biocides as counter ions of sodium sulfonate moieties incorporated into the Polymers, and surface antibacterial activity of the polyester films against Staphylococcus aureus and Escherichia coli was explored. These films exhibited a high surface antibacterial activity against S, aureus and E. coli, particularly against S. aureus, and the activity was affected by the structure and the compositional ratio of the phosphonium salts. Amount of the released phosphonium salts was very small, so that liberation of the phosphonium biocides can be expected to occur over a long period. Morphological changes of the cells of S. aureus and E. coli in contact with the polyester films were evaluated by scanning electron microscopy. It was found that the surface antibacterial activity of the polyester films was rather bacteriostatic than bactericidal as evidenced by no morphological changes of the bacterial cells in contact with the phosphonium biocides. (C) 1993 John Wiley & Sons, Inc.