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The potential benefit of stem cell therapy after stroke: an update

被引：43
作者：
Banerjee, Soma [1 ]
Williamson, Deborah A. [2 ]
Habib, Nagy [3 ]
Chataway, Jeremy [4 ,5 ]
机构：
[1] Imperial Coll Healthcare NHS Trust, Dept Stroke Med, London, England
[2] Univ Auckland, Dept Mol Med & Pathol, Auckland, New Zealand
[3] Imperial Coll London, Dept Surg, London, England
[4] Imperial Coll Healthcare NHS Trust, Clin Neurosci, London, England
[5] Univ Coll London Hosp NHS Fdn Trust, Natl Hosp Neurol & Neurosurg, London, England
来源：
VASCULAR HEALTH AND RISK MANAGEMENT | 2012年 / 8卷
关键词：
stroke; stem cells; clinical trials;
D O I：
10.2147/VHRM.S25745
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explore the challenges to making this a realistic treatment option for the future.
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收藏
页码：569 / 580
页数：12
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