Review of Clinical Applications of Fluorodeoxyglucose-PET/Computed Tomography in Pediatric Patients with Lymphoma

被引:3
作者
Cheng, Gang [1 ]
Akers, Scott R. [1 ]
Zhuang, Hongming [2 ]
Alavi, Abass [3 ]
机构
[1] Philadelphia VA Med Ctr, Dept Radiol, 3900 Woodland Ave, Philadelphia, PA 19104 USA
[2] Childrens Hosp Penn, Dept Radiol, Philadelphia, PA 19104 USA
[3] Hosp Univ Penn, Dept Radiol, Div Nucl Med, Philadelphia, PA 19102 USA
关键词
FDG-PET/CT; Lymphoma; Pediatrics; Diagnosis;
D O I
10.1016/j.cpet.2011.12.006
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];
摘要
[F-18] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) imaging is routinely used in the initial diagnosis and response assessment during and immediately after therapy, as well as in the follow-up surveillance. FDG PET/CT outperforms diagnostic CT and other conventional imaging modalities in the evaluation of pediatric patients with lymphoma, with higher sensitivity and specificity, leading to more accurate staging/restaging and modifications of therapeutic strategies. Resolution of FDG-avid lesions in the early post-therapy phase often indicates good response to treatment and better prognosis. FDG PET/CT also outperforms bone marrow biopsy in detecting bone marrow infiltration of lymphoma.
引用
收藏
页码:47 / +
页数:12
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