COMPLEMENT-FIXATION REACTIONS WTH COXSACKIE VIRUS AND ECHO VIRUS ANTIGENS

被引：5

作者：

POLZIN, EA

SCHMIDT, WAK

WIGAND, R

机构：

[1] Institut für Hygiene und Mikrobiologie der Universität des Saarlandes, Homburg (Saar)

来源：

ARCHIV FUR DIE GESAMTE VIRUSFORSCHUNG | 1969年 / 27卷 / 01期

关键词：

D O I：

10.1007/BF01250315

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The usefulness of serologically pure N antigens of several Coxsackie viruses and of ECHO-Virus 9 for diagnostic complement-fixation was studied with 70 paired sera from patients infected with enteroviruses. In homologous tests almost all sera showed positive reactions and mostly rises of titers. In heterologous reactions 6 out of 237 tests showed raising titers with N antigens, whereas 23 with mixed (N + H) antigens. Thus, the N antigens are superior to mixed antigens both in respect of sensitivity and specificity. The complement-fixation test with N antigens for diagnostic purposes appears to be only slightly inferior to the neutralization test. © 1969 Springer-Verlag.

引用

页码：65 / &

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