PREPARATION OF NUCLEOSIDES VIA ISOPROPYLIDENE SUGAR DERIVATIVES .4. SYNTHESIS OF 9-DELTA- AND 9-BETA-L-ERYTHROFURANOSYLADENINE

被引：5

作者：

LERNER, LM

机构：

[1] Department of Biochemistry, State University of New York, Doumstate Medical Center, Brooklyn

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1969年 / 34卷 / 01期

关键词：

D O I：

10.1021/jo00838a024

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,3-O-Isopropylidene-β-L-erythrofuranosyl chloride (1) was condensed with 6-benzamidochloromercuripurine and the blocking groups were removed to yield the anomers of 9-L-erythrofuranosyladenine (4) which were separated by column chromatography. In all experiments the β anomer (5) was the main product, leading to the conclusion that this condensation proceeded by an SN1 mechanism. © 1969, American Chemical Society. All rights reserved.

引用

页码：101 / &

共 19 条

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