PROLACTIN RECEPTOR IN HUMAN MAMMARY-CARCINOMA

被引：25

作者：

DICARLO, R

MUCCIOLI, G

机构：

来源：

TUMORI | 1979年 / 65卷 / 06期

关键词：

D O I：

10.1177/030089167906500605

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The specific binding of labelled human prolactin was determined in 83 human breast carcinomas. 27 tumors (32.5%) contained specific binding for prolactin of at least 1% and were considered prolactin receptor positive. The binding was found linearly related to membrane protein concentration and specific only for lactogenic hormones. By Scatchard analysis the dissociation constant appeared similar to that observed in other target tisues, with a low binding capacity.

引用

页码：695 / 702

页数：8

共 17 条

[1] LABELING OF PROTEINS TO HIGH SPECIFIC RADIOACTIVITIES BY CONJUGATION TO A I-125-CONTAINING ACYLATING AGENT - APPLICATION TO RADIOIMMUNOASSAY [J].