ANALYSIS OF LONGITUDINAL RELAXATION RATE CONSTANTS FROM MAGNETIZATION TRANSFER MR IMAGES OF HUMAN TISSUES AT 0.1-T

被引:14
作者
KOMU, M
机构
[1] Department of Diagnostic Radiology, University of Turku
关键词
MUSCLE MRI; MAGNETIZATION TRANSFER CONTRAST;
D O I
10.1016/0730-725X(92)90370-F
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];
摘要
The human calf muscle was examined by using the magnetization transfer MR imaging technique. The time-dependent saturation transfer (TDST) method was applied at low magnetic field 0.1 T in order to measure the mobile water relaxation time T1w, the magnetization transfer rate R(wm) from water to solid macromolecules, and the magnetization transfer contrast (MTC) of the human tissue. The magnetization transfer contrast of 0.67 was attained. The transfer rate R(wm) was 4.5 sec-1 (+/- 0.3 sec-1) for the anterior tibial muscle and 5.0 sec-1 (+/- 0.4 sec-1) for the gastrocnemius muscles. The values of R(wm) are considerably larger than the values of corresponding relaxation rates measured at high fields. The relaxation rate measurements of human tissues in vivo was shown to be possible at 0.1 T even within the framework of normal routine MR imaging. Magnetization transfer MR imaging is a very promising and practical method in order to assess the relaxation processes in heterogeneous human tissues in vivo, and it can improve the tissue characterization possibilities of MR imaging techniques.
引用
收藏
页码:35 / 40
页数:6
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