MICROBIOLOGICAL SYNTHESIS OF OPTICALLY-ACTIVE (2R,3S)-2,3-DEUTERIO-CYCLOHEXAN-1-ONES AND (2R,3S)-2-METHYL-3-DEUTERIOCYCLOHEXAN-1-ONE - ENANTIOSPECIFIC ANTI-ADDITION OF HYDROGEN TO THE DOUBLE-BOND OF CYCLOHEX-2-EN-1-ONES

被引：6

作者：

DAUPHIN, G

GOURCY, JG

VESCHAMBRE, H

机构：

[1] Laboratoire de Chimie Organique Biologique, URA 485 du CNRS

来源：

TETRAHEDRON-ASYMMETRY | 1992年 / 3卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(00)82289-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Addition of hydrogen to the double bond of cyclohexenones during microbiological reduction by Beauveria sulfurescens gives the trans product in high yield (90%) resulting from anti-addition to the si face on C-2 and the re face on C-3.

引用

页码：595 / 598

页数：4

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