ANALYSIS OF THE CONTRAST AGENT IOPAMIDOL IN SERUM BY CAPILLARY ELECTROPHORESIS

被引：9

作者：

SHIHABI, ZK

ROCCO, MV

HINSDALE, ME

机构：

[1] Pathology Department, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1995年 / 18卷 / 18-19期

关键词：

D O I：

10.1080/10826079508014627

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A rapid method for the analysis of the contrast agent iopamidol (isovue) in serum by CE is described. The method involves deproteinzation with acetonitrile to remove serum proteins followed by direct capillary zone electrophoresis. It is rapid (about 10 min) and sensitive. Other contrast agents and compounds used for renal function tests such as iohexol, iothalamic acid and p-aminohippuric acid can be detected by the same method. The use of acetonitrile in this method to remove serum proteins results in sample stacking allowing the detection of levels less than 1 mg/L.

引用

页码：3825 / 3831

页数：7

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