THE USE OF LABORATORY METHODS IN CONTACT-DERMATITIS INDUCED BY COMPOSITE-MATERIALS

被引：6

作者：

AYALA, F ^{[1
]}

LEMBO, G ^{[1
]}

BALATO, N ^{[1
]}

PATRUNO, C ^{[1
]}

SCOGNAMIGLIO, G ^{[1
]}

STRAZZULLO, G ^{[1
]}

DESTEFANO, S ^{[1
]}

机构：

[1] CNR,IST CHIM MOLEC INTERESSE BIOL,NAPLES,ITALY

来源：

CONTACT DERMATITIS | 1990年 / 22卷 / 05期

关键词：

aircraft industry; chromatography; colophony; contact allergy; epoxy resin; mass spectrometry; nuclear magnetic resonance; occupational; phenylglycidyl ether; tetraglycidyl‐4,4‐dimythyl aniline; triglycidyl‐p‐aminophenol;

D O I：

10.1111/j.1600-0536.1990.tb01593.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 [免疫学];

摘要：

Thin‐layer chromatography, column chromatography, new spectrometry and nuclear magnetic resonance were used to investigate the chemical constituents and haptens responsible in 2 different circumstances where allergic contact dermatitis from composite materials was suspected. In an aircraft factory where epoxy resins were used, tetraglycidyl‐4,4‐dimythyl dianiline and phenylglycidyl ether were identified as the haptens responsible for an outbreak of contact dermatitis. The role of abietic acid as the main sensitizer in colophony was confirmed in a case of contact dermatitis occurring in a sportsman with an acute eczematous reaction due to a leg bandage. Identification of the chemical sensitizers was possible only by using the aforementioned laboratory methods. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：262 / 266

页数：5

共 7 条

[1]

CONTACT-DERMATITIS FROM THE EPOXY-RESINS TETRAGLYCIDYL-4,4'-METHYLENE DIANILINE AND ORTHO-DIGLYCIDYL PHTHALATE IN COMPOSITE-MATERIAL [J].