NO INFLUENCE OF AGE ON THE ILEAL ABSORPTION OF BILE-ACIDS IN HUMANS AS DETERMINED BY THE SEHCAT TEST

被引：6

作者：

EUSUFZAI, S

ERICSSON, S

CEDERLUND, T

EINARSSON, K

ANGELIN, B

机构：

[1] Metabolism Unit and Division of Castroenterology, Department of Medicine, Karolinska Institute, Huddinge University Hospital, Huddinge

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 1993年 / 5卷 / 04期

关键词：

AGE; SELENOHOMOCHOLIC ACID TAURINE (SEHCAT); CHOLIC ACID; CHENODEOXYCHOLIC ACID; DEOXYCHOLIC ACID; CHOLESTEROL;

D O I：

10.1097/00042737-199304000-00009

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Objective: To determine the influence of age on ileal absorption of bile acids. Design: Bile acid absorption was evaluated with the gamma-emitting bile acid analogue, selenohomocholic acid taurine (SeHCAT) in 11 healthy young (aged 35 years or less) and 11 healthy elderly subjects (aged 65 years or more). Method: SeHCAT was given orally and its fractional catabolic rate (FCR) and 7-day retention were assessed by repeated external counting for the following 7 days. Fasting serum was also analysed for the lipid profile. Results: No significant difference was found between the two groups despite a significant increase in serum total and low density lipoprotein cholesterol with age. Conclusions: We could not observe any influence of age on bile acid absorption evaluated with the SeHCAT test.

引用

页码：247 / 249

页数：3

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