PRE-COLUMBIAN TUBERCULOSIS IN NORTHERN CHILE - MOLECULAR AND SKELETAL EVIDENCE

被引:96
作者
ARRIAZA, BT
SALO, W
AUFDERHEIDE, AC
HOLCOMB, TA
机构
[1] UNIV TARAPACA,ARICA,CHILE
[2] UNIV MINNESOTA,DEPT BIOCHEM & MOLEC BIOL,DULUTH,MN 55812
[3] UNIV MINNESOTA,DEPT PATHOL,PALEOBIOL LAB,DULUTH,MN 55812
关键词
POTTS DISEASE; DNA; MUMMY; ANDES;
D O I
10.1002/ajpa.1330980104
中图分类号
Q98 [人类学];
学科分类号
030303 ;
摘要
Analysis of 483 skeletons from Arica (Chile) and review of mummy dissection records demonstrates an overall 1% prevalence rate for tuberculosis between 2000 B.C. and A.D. 1500. Tuberculosis cases cluster in the period A.D. 500-1000 which correlates with fully agropastoral societies. Considering only these agropastoral societies, about 2% of their members show tuberculosis lesions. A segment of DNA unique to Mycobacterium tuberculosis was identified in an extract from the vertebral lesion of a 12-year-old girl with Pott's disease from about A.D. 1000, establishing the pre-Columbian presence of tuberculosis with the most specific evidence currently available. (C) 1995 Wiley-Liss, Inc.
引用
收藏
页码:37 / 45
页数:9
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