SINGLE ORAL TREATMENT WITH MEBENDAZOLE FOR THE CONTROL OF TAENIA-CRASSICEPS LARVAL INFECTIONS IN RATS

被引：6

作者：

HEATH, DD

LAWRENCE, SB

机构：

[1] Wallaceville Animal Research Centre, Research Division, Ministry of Agriculture and Fisheries, P.B. Upper Hutt

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1979年 / 9卷 / 01期

关键词：

levamisole; Mebendazole; rats; Taenia crassiceps;

D O I：

10.1016/0020-7519(79)90070-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

A single oral treatment with mebendazole for the control of Taenia crassiceps larval infections in rats. International Journal for Parasitology 9: 73-76. Rats infected with Taenia crassiceps larvae were treated with mebendazole. At a sublethal dose level of 50 mg/kg, a single large oral treatment proved to be markedly more effective in killing cysts than the same amount of drug divided into 10 daily smaller doses. Levamisole promoted a vigorous host cellular response to the intraperitoneal cysts, but when incorporated with mebendazole, it did not enhance the action of the latter drug. © 1979.

引用

页码：73 / 76

页数：4

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