DETERMINATION OF TRYPTOPHAN AND 10 OF ITS METABOLITES IN A SINGLE ANALYSIS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH MULTIPLE DETECTION

被引：8

作者：

CARUSO, U ^{[1
]}

FOWLER, B ^{[1
]}

MINNITI, G ^{[1
]}

ROMANO, C ^{[1
]}

机构：

[1] UNIV BASEL,CHILDRENS HOSP,BASEL,SWITZERLAND

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 661卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(94)85181-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Tryptophan is an essential amino acid whose metabolism involves several pathways. Defects, either inherited or functional, in its transport mechanism or catabolism are related to a large variety of clinical abnormalities. This paper presents a relatively simple and rapid method to determine quantitatively tryptophan and several of its metabolites in biological fluids using reversed-phase high-performance liquid chromatography and multiple detection.

引用

页码：101 / 104

页数：4

共 6 条

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[5] ANALYSIS OF TRYPTOPHAN AND ITS METABOLITES BY REVERSE-PHASE HIGH-PRESSURE LIQUID-CHROMATOGRAPHY
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