ONLINE BLOOD ELECTROLYTE MONITORING WITH A CHEMFET MICROCELL SYSTEM

被引：29

作者：

GUMBRECHT, W ^{[1
]}

SCHELTER, W ^{[1
]}

MONTAG, B ^{[1
]}

RASINSKI, M ^{[1
]}

PFEIFFER, U ^{[1
]}

机构：

[1] KLIN RECHTS ISAR,INST EXPTL CHIRURG,W-8000 MUNICH,GERMANY

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 1990年 / 1卷 / 1-6期

关键词：

blood electrolytes; blood pH; ChemFET; flow-through cell; ISFET; online monitoring;

D O I：

10.1016/0925-4005(90)80253-V

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A sample-taking sensor system for online pH and electrolyte monitoring of blood is described. The system consists of a two-lumen catheter with a ChemFET flow-through cell, a syringe pump unit with ChemFET instrumentation and a personal computer. Suitable operation of the pump unit allows the sensor to be calibrated every 2 min before each measurement. The blood sample volume withdrawn from the patient is on the order of 10 μl. Solvent polymeric membrane ISFETs serve as measurement sensors as well as reference sensors. For this purpose they are spatially separated by a flow-through channel where a liquid junction can be established between the calibration solution and blood. In this way the arrangement saves a conventional reference electrode with the bridge solution. In vivo experiments in pigs show a very good correlation between sensor and analyzer values. There was no blood clotting in the sensor system. © 1990.

引用

页码：477 / 480

页数：4

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