SUITABILITY OF COLLECTION TUBES WITH SEPARATOR GELS FOR THERAPEUTIC DRUG-MONITORING

被引：36

作者：

KOCH, TR

PLATOFF, G

机构：

[1] Department of Pathology, University of Maryland School of Medicine, Baltimore, MD

来源：

THERAPEUTIC DRUG MONITORING | 1990年 / 12卷 / 03期

关键词：

Serum drug monitoring; Specimen collection; Specimen storage;

D O I：

10.1097/00007691-199005000-00011

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The purpose of this study was to determine the suitability of four collection tubes containing separation gels for collection of specimens for 15 therapeutic drugs. To blood tubes from drug-free volunteers, selected drugs were added and measured after centrifugation and storage for 6, 24, and 72 h in the collection tube. We found that the Becton Dickinson SST tube extracted phenytoin even with immediate separation of serum. For prolonged storage, the SST tube was unsuitable for quinidine (>24 h) and lidocaine (>6 h); the Monoject Corvac was unsuitable for lidocaine (any storage). Partially filled tubes caused additional errors. Completely filled Terumo Autosep and Monoject Corvac tubes are satisfactory for all drugs tested if serum is removed promptly. © 1990 Raven Press, Ltd., New York.

引用

页码：277 / 280

页数：4

共 8 条

[1] STABILITY OF DRUG CONCENTRATIONS IN PLASMA STORED IN SERUM SEPARATOR BLOOD COLLECTION TUBES [J].