DNA PROBE DETECTION OF EIKENELLA-CORRODENS, WOLINELLA-RECTA AND FUSOBACTERIUM-NUCLEATUM IN SUBGINGIVAL PLAQUE

被引：24

作者：

LIPPKE, JA ^{[1
]}

PEROS, WJ ^{[1
]}

KEVILLE, MW ^{[1
]}

SAVITT, ED ^{[1
]}

FRENCH, CK ^{[1
]}

机构：

[1] BIOTECHN DIAGNOST,61 MOULTON ST,CAMBRIDGE,MA 02138

来源：

ORAL MICROBIOLOGY AND IMMUNOLOGY | 1991年 / 6卷 / 02期

关键词：

DNA PROBE; PERIODONTAL PATHOGEN; EIKENELLA-CORRODENS; WOLINELLA-RECTA; FUSOBACTERIUM-NUCLEATUM; SUBGINGIVAL PLAQUE;

D O I：

10.1111/j.1399-302X.1991.tb00456.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

This cross-sectional study used species-specific DNA probes to examine subgingival plaque specimens for the presence of Eikenella corrodens, Wolinella recta, and Fusobacterium nucleatum in adults with untreated periodontitis or gingivitis and in healthy controls. W. recta and F. nucleatum were more prevalent in diseased sites from the periodontitis group when compared with the controls (81% vs 22% and 83% vs 20% respectively). E. corrodens was detected in 62% of the control sites and 81% of the periodontitis sites. Because the control sites commonly contained this organism, E. corrodens may not be useful in differentiating between health and disease. In addition, the relationship between the prevalence of W. recta and F. nucleatum and the prevalence of the established periodontal pathogens, Actinobacillus actinomycetemcomitans, Bacteroides intermedius and Bacteroides gingivalis, was examined. Positive detection of W. recta and F. nucleatum correlated closely with the presence of A. actinomycetemcomitans, B. intermedius and B. gingivalis. Therefore, W. recta and F. nucleatum do not appear to be unique indicators of periodontal disease.

引用

页码：81 / 87

页数：7

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