SYNTHESIS OF 22,23-EPOXYVITAMIN-D2 (22,23-EPOXYERGOCALCIFEROL)

被引：12

作者：

TADA, M

OIKAWA, A

机构：

[1] Research Institute for Tuberculosis and Cancer, Tohoku University, Sendai 980

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1979年 / 07期

关键词：

D O I：

10.1039/p19790001858

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heating Diels-Alder adducts of steroidal-5,7-dienes and 4-phenyl-1,2,4-triazoline-3,5-dione with mineral base in an appropriate solvent at 120 °C gives the corresponding steroidal-5,7-dienes in high yields. This method is applied to a synthesis of 22,23-epoxyergosterols. The irradiation of this compound followed by thermal isomerization gives 22,23-epoxyvitamin D 2.

引用

页码：1858 / 1861

页数：4

共 15 条

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