A CASE OF CEREBELLAR MEDULLOBLASTOMA WITH A SINGLE CHROMOSOME ABNORMALITY

被引：13

作者：

STRATTON, MR

DARLING, J

COOPER, CS

REEVES, BR

机构：

[1] INST NEUROL,GOUGH COOPER DEPT NEUROL SURG,NEUROONCOL SECT,LONDON WC1N 3BG,ENGLAND

[2] INST CANC RES,CHESTER BEATTY LABS,CHEM CARCINOGENESIS SECT,LONDON,ENGLAND

[3] INST CHILD HLTH,LEUKAEMIA RES FUND,CTR CHILDHOOD LEUKAEMIA,DEPT HAEMATOL & ONCOL,BIRMINGHAM B16 8ET,W MIDLANDS,ENGLAND

来源：

CANCER GENETICS AND CYTOGENETICS | 1991年 / 53卷 / 01期

关键词：

D O I：

10.1016/0165-4608(91)90120-J

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In the few published karyotypes of human medulloblastoma, multiple chromosome abnormalities have usually been demonstrated. We report a case of medulloblastoma in which only a single structural alteration was observed, namely an unbalanced translocation between chromosomes 1 and 6 resulting in partial 1q trisomy and partial 6q monosomy. This finding may help define genomic regions that are of importance in development of medulloblastoma.

引用

页码：101 / 103

页数：3

共 12 条

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