UREA PRODUCTION FROM LABELLED AMMONIA IN ARGININOSUCCINIC ACIDURIA

被引：13

作者：

CRANE, CW

GAY, WMB

JENNER, FA

机构：

[1] Wellcome Research Laboratories, Department of Medicine, Queen Elizabeth Hospital, Edgbaston, Birmingham

来源：

CLINICA CHIMICA ACTA | 1969年 / 24卷 / 03期

关键词：

D O I：

10.1016/0009-8981(69)90118-1

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The formation of urea from orally administered 15N-labelled ammonium lactate has been studied in a patient with argininosuccinic aciduria. Compared with data from a similar experiment with a normal subject the synthesis of isotopic urea was not grossly depressed. After three days the patient retained more 15N than the control and this suggested that in consequence of the block in urea formation an abnormally large fraction of the [15N]ammonium was metabolised to glutamine. © 1969.

引用

页码：445 / &

共 9 条

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