CORTISOL HYPER-SECRETION IN PREPUBERTAL DEPRESSIVE-ILLNESS - PRELIMINARY-REPORT

被引：59

作者：

PUIGANTICH, J ^{[1
]}

CHAMBERS, W ^{[1
]}

HALPERN, F ^{[1
]}

HANLON, C ^{[1
]}

SACHAR, EJ ^{[1
]}

机构：

[1] NEW YORK STATE PSYCHIAT INST,NEW YORK,NY 10032

来源：

PSYCHONEUROENDOCRINOLOGY | 1979年 / 4卷 / 03期

关键词：

D O I：

10.1016/0306-4530(79)90002-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

(1) Plasma cortisol was measured every 20 min for 10-24 hr in 4 prepubertal children fitting unmodified Research Diagnostic Criteria (RDC) for major depressive disorder, endogenous subtype. (2) Hormonal assessments were made before treatment and after clinical recovery. (3) Two of the 4 subjects presented evidence of cortisol hypersecretion during illness, subsiding after clinical recovery, similar to that seen in adult endogenous depressives. (4) These preliminary data support the hypothesis that child and adult major depressive disorders are basically the same illness occurring at different points in development. © 1979.

引用

页码：191 / 197

页数：7

共 17 条

[1]

CARROLL BJ, 1976, ARCH GEN PSYCHIAT, V33, P1051

[2]

CARROLL BJ, 1976, ARCH GEN PSYCHIAT, V33, P1039

[3]

CARROLL BJ, 1976, HORMONES BEHAVIOR PS, P193

[4]

CARROLL BJ, 1978, PSYCHOPHARMACOLOGY G, P487

[5]

GIBBONS JL, 1964, ARCH GEN PSYCHIAT, V10, P572

[6] CORTISOL IS SECRETED EPISODICALLY BY NORMAL MAN [J].

HELLMAN, L ;

NAKADA, F ;

CURTI, J ;

WEITZMAN, ED ;

KREAM, J ;

ROFFWARG, H ;

ELLMAN, S ;

FUKUSHIM.DK ;

GALLAGHE.TF .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1970, 30 (04) :411-+

[7]

Kovacs M., 1977, DEPRESSION CHILDHOOD, P1

[8] SOME STUDIES OF PROTEIN-BINDING OF STEROIDS AND THEIR APPLICATION TO ROUTINE MICRO AND ULTRAMICRO MEASUREMENT OF VARIOUS STEROIDS IN BODY FLUIDS BY COMPETITIVE PROTEIN-BINDING RADIOASSAY [J].

MURPHY, BEP .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1967, 27 (07) :973-+

[9]

PEARCE JB, CHILD PSYCHIATRY MOD, P448

[10]

PEARCE JB, 1977, THESIS U LONDON

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