N-2-ISOBUTYRL-O-6-[2-(PARA-NITROPHENYL)ETHYL]GUANINE - A NEW BUILDING BLOCK FOR THE EFFICIENT SYNTHESIS OF CARBOCYCLIC GUANOSINE ANALOGS

被引：50

作者：

JENNY, TF ^{[1
]}

SCHNEIDER, KC ^{[1
]}

BENNER, SA ^{[1
]}

机构：

[1] SWISS FED INST TECHNOL,ORGAN CHEM LAB,CH-8092 ZURICH,SWITZERLAND

来源：

NUCLEOSIDES & NUCLEOTIDES | 1992年 / 11卷 / 06期

关键词：

D O I：

10.1080/07328319208018340

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

N2-Isobutyryl-O6-[2-(p-nitrophenyl)ethyl]guanine (4) allows the synthesis of different types of carbocyclic analogs of guanosine in high yield under Mitsunobu conditions. Only the desired N-9-substituted derivatives of guanine are formed.

引用

页码：1257 / 1261

页数：5

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