STUDIES ON PYRROLIDONES - SYNTHESIS AND N-ALKYLATION OF BETA-ENAMINOESTERS DERIVED FROM PYROGLUTAMIC ACID

被引：31

作者：

FASSEUR, D

RIGO, B

LEDUC, C

CAULIEZ, P

COUTURIER, D

机构：

[1] ECOLE HAUTES ETUD IND,SYNTH ORGAN LAB,F-59046 LILLE,FRANCE

[2] UNIV SCI & TECH LILLE & FLANDRES ARTOIS,SYNTH ORGAN LAB,F-59655 VILLENEUVE DASCQ,FRANCE

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1992年 / 29卷 / 05期

关键词：

D O I：

10.1002/jhet.5570290537

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The condensation of iminoether 7, derived from pyroglutamic acid (4), with active methylene reagents such as Meldrum's acid or methyl cyanoacetate, lead to beta-enaminoesters 2. Solid-liquid phase transfer N-alkylation of these compounds is described.

引用

页码：1285 / 1291

页数：7

共 47 条

[1]

ANDERSEN TP, 1986, LIEBIGS ANN CHEM, P269

[2]

AZIMOV VA, 1978, CHEM HETEROCYCLIC CO, P289

[3] SYNTHESIS OF THE CARBAPENAM SYSTEM FROM GLUTAMIC-ACID AND ACETOACETIC ACID-DERIVATIVES [J].