CALCIUM-BINDING PROPERTIES OF RABBIT LIVER PROTEIN DISULFIDE-ISOMERASE

被引：43

作者：

LEBECHE, D ^{[1
]}

LUCERO, HA ^{[1
]}

KAMINER, B ^{[1
]}

机构：

[1] BOSTON UNIV,SCH MED,DEPT PHYSIOL,BOSTON,MA 02118

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 202卷 / 01期

关键词：

D O I：

10.1006/bbrc.1994.1964

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have characterized the Ca2+ binding properties of protein disulfide isomerase (PDI). It binds 19 mol Ca2+/mol protein with low affinity, which is reduced by increasing the ionic strength. Ca2+ induced conformational changes detected by UV difference spectroscopy. These Ca2+ binding properties resemble those of a sea urchin egg 58 kDa protein. (C) 1994 Academic Press, Inc.

引用

页码：556 / 561

页数：6

共 31 条

[1] ACTIVITY-DEPENDENT ACCUMULATION OF CALCIUM IN PURKINJE-CELL DENDRITIC SPINES [J].